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Universal genome-wide association studies: Powerful joint ancestry and association testing

The vast majority of human populations and individuals have mixed ancestry. Consequently, adjustment for locus-specific ancestry is essential for genetic association studies. To empower association studies for all populations, it is necessary to integrate effects of locus-specific ancestry and genot...

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Detalles Bibliográficos
Autores principales: Shriner, Daniel, Bentley, Amy R., Gouveia, Mateus H., Heuston, Elisabeth F., Doumatey, Ayo P., Chen, Guanjie, Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507155/
https://www.ncbi.nlm.nih.gov/pubmed/37653728
http://dx.doi.org/10.1016/j.xhgg.2023.100235