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CD47 blockade enhances phagocytosis of cardiac cell debris by neutrophils

CD47 is a cell surface protein controlling phagocytotic activity of innate immune cells. CD47 blockade was investigated as an immune checkpoint therapy in cancer treatment, enhancing phagocytosis of tumor cells by macrophages. Anti-CD47 treatment also reduced injury size during reperfused acute myoc...

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Detalles Bibliográficos
Autores principales: Haj-Yehia, Elias, Korste, Sebastian, Jochem, Robert, Lusha, Aldona, Roth, Anna, Dietzel, Nina, Niroomand, Josefine, Stock, Pia, Westendorf, Astrid M., Buer, Jan, Hendgen-Cotta, Ulrike B., Rassaf, Tienush, Totzeck, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507185/
https://www.ncbi.nlm.nih.gov/pubmed/37731517
http://dx.doi.org/10.1016/j.ijcha.2023.101269