Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of Staphylococcus aureus

Life-threatening toxic shock syndrome is often caused by the superantigen toxic shock syndrome toxin-1 (TSST-1) produced by Staphylococcus aureus. A well-known risk factor is the lack of neutralizing antibodies. To identify determinants of the anti-TSST-1 antibody response, we examined 976 participa...

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Detalles Bibliográficos
Autores principales: Weiss, Stefan, Holtfreter, Silva, Meyer, Tanja C., Schmiedeke, Frieder, Cammann, Clemens, Dörr, Marcus, Felix, Stephan B., Grabe, Hans J., Homuth, Georg, Kohler, Christian, Mahncke, Cedric, Michalik, Stephan, Nauck, Matthias, Friedrich, Nele, Samietz, Stefanie, Völzke, Henry, Völker, Uwe, Bröker, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507260/
https://www.ncbi.nlm.nih.gov/pubmed/37731490
http://dx.doi.org/10.3389/fimmu.2023.1229562

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