Population pharmacokinetics of Amisulpride in Chinese patients with schizophrenia with external validation: the impact of renal function

Introduction: Amisulpride is primarily eliminated via the kidneys. Given the clear influence of renal clearance on plasma concentration, we aimed to explicitly examine the impact of renal function on amisulpride pharmacokinetics (PK) via population PK modelling and Monte Carlo simulations. Method: P...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Anning, Mak, Wen Yao, Ruan, Tingyi, Dong, Fang, Zheng, Nan, Gu, Meng, Guo, Wei, Zhang, Jingye, Cheng, Haoxuan, Ruan, Canjun, Shi, Yufei, Zang, Yannan, Zhu, Xuequan, He, Qingfeng, Xiang, Xiaoqiang, Wang, Gang, Zhu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507317/
https://www.ncbi.nlm.nih.gov/pubmed/37731733
http://dx.doi.org/10.3389/fphar.2023.1215065

Ejemplares similares

Ejemplares similares