Novel engineered B lymphocytes targeting islet-specific T cells inhibit the development of type 1 diabetes in non-obese diabetic Scid mice

INTRODUCTION: In this study, we report a novel therapeutic approach using B lymphocytes to attract islet-specific T cells in the non-obese diabetic (NOD) mouse model and prevent the development of autoimmune diabetes. Rather than using the antibody receptor of B cells, this approach utilizes their p...

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Detalles Bibliográficos
Autores principales: Chen, Dawei, Kakabadse, Dimitri, Fishman, Sigal, Weinstein-Marom, Hadas, Davies, Joanne, Boldison, Joanne, Thayer, Terri C., Wen, Li, Gross, Gideon, Wong, F. Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507356/
https://www.ncbi.nlm.nih.gov/pubmed/37731505
http://dx.doi.org/10.3389/fimmu.2023.1227133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507356/
https://www.ncbi.nlm.nih.gov/pubmed/37731505
http://dx.doi.org/10.3389/fimmu.2023.1227133

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