Cargando…

Rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: A case report

BACKGROUND: Anticoagulation treatment after lower limb surgery is one of the key methods to avoid thrombosis, and low-molecular-weight heparin is the treatment that is most frequently used in clinical practice. But one uncommon side effect of low-molecular-weight heparin is heparin-induced thrombocy...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Fang-Fang, Li, Mei-Ye, Qu, Wei, Jiang, Zhao-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507566/
https://www.ncbi.nlm.nih.gov/pubmed/37731576
http://dx.doi.org/10.12998/wjcc.v11.i26.6147
_version_ 1785107345821401088
author Lv, Fang-Fang
Li, Mei-Ye
Qu, Wei
Jiang, Zhao-Shun
author_facet Lv, Fang-Fang
Li, Mei-Ye
Qu, Wei
Jiang, Zhao-Shun
author_sort Lv, Fang-Fang
collection PubMed
description BACKGROUND: Anticoagulation treatment after lower limb surgery is one of the key methods to avoid thrombosis, and low-molecular-weight heparin is the treatment that is most frequently used in clinical practice. But one uncommon side effect of low-molecular-weight heparin is heparin-induced thrombocytopenia (HIT), which can develop into thrombosis if not caught early or managed incorrectly. CASE SUMMARY: We present a case of a patient who underwent hip arthroplasty and experienced thrombocytopenia due to HIT on the 9(th) d following the application of low-molecular-weight heparin anticoagulation. We did not diagnose HIT in time and applied 1 unit of platelets to the patient, which led to thrombosis. Luckily, the patient recovered following effective and timely surgery and treatment with rivaroxaban. CONCLUSION: Patients using low-molecular-weight heparin after lower limb surgery need to have their platelet counts regularly checked. If HIT develops, platelet treatment should be given with caution.
format Online
Article
Text
id pubmed-10507566
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Baishideng Publishing Group Inc
record_format MEDLINE/PubMed
spelling pubmed-105075662023-09-20 Rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: A case report Lv, Fang-Fang Li, Mei-Ye Qu, Wei Jiang, Zhao-Shun World J Clin Cases Case Report BACKGROUND: Anticoagulation treatment after lower limb surgery is one of the key methods to avoid thrombosis, and low-molecular-weight heparin is the treatment that is most frequently used in clinical practice. But one uncommon side effect of low-molecular-weight heparin is heparin-induced thrombocytopenia (HIT), which can develop into thrombosis if not caught early or managed incorrectly. CASE SUMMARY: We present a case of a patient who underwent hip arthroplasty and experienced thrombocytopenia due to HIT on the 9(th) d following the application of low-molecular-weight heparin anticoagulation. We did not diagnose HIT in time and applied 1 unit of platelets to the patient, which led to thrombosis. Luckily, the patient recovered following effective and timely surgery and treatment with rivaroxaban. CONCLUSION: Patients using low-molecular-weight heparin after lower limb surgery need to have their platelet counts regularly checked. If HIT develops, platelet treatment should be given with caution. Baishideng Publishing Group Inc 2023-09-16 2023-09-16 /pmc/articles/PMC10507566/ /pubmed/37731576 http://dx.doi.org/10.12998/wjcc.v11.i26.6147 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Lv, Fang-Fang
Li, Mei-Ye
Qu, Wei
Jiang, Zhao-Shun
Rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: A case report
title Rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: A case report
title_full Rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: A case report
title_fullStr Rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: A case report
title_full_unstemmed Rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: A case report
title_short Rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: A case report
title_sort rivaroxaban for the treatment of heparin-induced thrombocytopenia with thrombosis in a patient undergoing artificial hip arthroplasty: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507566/
https://www.ncbi.nlm.nih.gov/pubmed/37731576
http://dx.doi.org/10.12998/wjcc.v11.i26.6147
work_keys_str_mv AT lvfangfang rivaroxabanforthetreatmentofheparininducedthrombocytopeniawiththrombosisinapatientundergoingartificialhiparthroplastyacasereport
AT limeiye rivaroxabanforthetreatmentofheparininducedthrombocytopeniawiththrombosisinapatientundergoingartificialhiparthroplastyacasereport
AT quwei rivaroxabanforthetreatmentofheparininducedthrombocytopeniawiththrombosisinapatientundergoingartificialhiparthroplastyacasereport
AT jiangzhaoshun rivaroxabanforthetreatmentofheparininducedthrombocytopeniawiththrombosisinapatientundergoingartificialhiparthroplastyacasereport