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A drug repurposing method based on inhibition effect on gene regulatory network

Numerous computational drug repurposing methods have emerged as efficient alternatives to costly and time-consuming traditional drug discovery approaches. Some of these methods are based on the assumption that the candidate drug should have a reversal effect on disease-associated genes. However, suc...

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Detalles Bibliográficos
Autores principales: Li, Xianbin, Liao, Minzhen, Wang, Bing, Zan, Xiangzhen, Huo, Yanhao, Liu, Yue, Bao, Zhenshen, Xu, Peng, Liu, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507583/
https://www.ncbi.nlm.nih.gov/pubmed/37731599
http://dx.doi.org/10.1016/j.csbj.2023.09.007