Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children

BACKGROUND AND AIM: Hepatic phase I drug-metabolizing enzymes CYP2E1, CYP1A2 and CYP3A4 catalyze the biotransformation of Acetaminophen (APAP) and are important in the mediation of toxicity. The potential role of other hepatic and non-hepatic Phase I enzymes in APAP toxicity has not been established...

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Detalles Bibliográficos
Autores principales: McCullough, Sandra, Dweep, Harsh, McGill, Mitchell R., Bhattacharyya, Sudeepa, James, Laura, Frankowski, Sara, Woodall, Aaron, Kearns, Gregory, Gill, Pritmohinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507677/
https://www.ncbi.nlm.nih.gov/pubmed/31393259
http://dx.doi.org/10.2174/2211536608666190808144456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507677/
https://www.ncbi.nlm.nih.gov/pubmed/31393259
http://dx.doi.org/10.2174/2211536608666190808144456

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