Impact of sex on the efficacy and safety of panitumumab plus fluorouracil and folinic acid versus fluorouracil and folinic acid alone as maintenance therapy in RAS WT metastatic colorectal cancer (mCRC). Subgroup analysis of the PanaMa-study (AIO-KRK-0212)

BACKGROUND: Clinical trials in metastatic colorectal cancer (mCRC) are usually conducted irrespective of sex. Sex-associated differences relating to safety and efficacy in the treatment of mCRC, however, are gaining interest. METHODS: PanaMa investigated the efficacy of panitumumab (Pmab) plus fluor...

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Detalles Bibliográficos
Autores principales: Heinrich, K., Karthaus, M., Fruehauf, S., Graeven, U., Mueller, L., König, A.O., von Weikersthal, L. Fischer, Caca, K., Kretzschmar, A., Goekkurt, E., Haas, S., Alig, A.H.S., Kurreck, A., Stahler, A., Held, S., Sommerhäuser, G., Heinemann, V., Stintzing, S., Trarbach, T., Modest, D.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507735/
https://www.ncbi.nlm.nih.gov/pubmed/37441876
http://dx.doi.org/10.1016/j.esmoop.2023.101568

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