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Comparison of Huntington’s disease phenotype progression in male and female heterozygous FDNQ175 mice
Huntington’s Disease (HD) is an inherited autosomal dominant neurodegenerative disorder that leads to progressive motor and cognitive impairment due to the expansion of a polyglutamine (CAG) repeat in the N-terminal region of the huntingtin (Htt) protein. The creation of HD mouse models represents a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508000/ https://www.ncbi.nlm.nih.gov/pubmed/37726802 http://dx.doi.org/10.1186/s13041-023-01054-6 |