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Comparison of Huntington’s disease phenotype progression in male and female heterozygous FDNQ175 mice

Huntington’s Disease (HD) is an inherited autosomal dominant neurodegenerative disorder that leads to progressive motor and cognitive impairment due to the expansion of a polyglutamine (CAG) repeat in the N-terminal region of the huntingtin (Htt) protein. The creation of HD mouse models represents a...

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Detalles Bibliográficos
Autores principales:	Li, Si Han, Colson, Tash-Lynn L., Chen, Jingwei, Abd-Elrahman, Khaled S., Ferguson, Stephen S. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508000/ https://www.ncbi.nlm.nih.gov/pubmed/37726802 http://dx.doi.org/10.1186/s13041-023-01054-6

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