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Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome

BACKGROUND: The proteome is a major source of therapeutic targets. We conducted a proteome-wide Mendelian randomization (MR) study to identify candidate protein markers and therapeutic targets for colorectal cancer (CRC). METHODS: Protein quantitative trait loci (pQTLs) were derived from seven publi...

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Detalles Bibliográficos
Autores principales:	Sun, Jing, Zhao, Jianhui, Jiang, Fangyuan, Wang, Lijuan, Xiao, Qian, Han, Fengyan, Chen, Jie, Yuan, Shuai, Wei, Jingsun, Larsson, Susanna C., Zhang, Honghe, Dunlop, Malcolm G, Farrington, Susan M, Ding, Kefeng, Theodoratou, Evropi, Li, Xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508028/ https://www.ncbi.nlm.nih.gov/pubmed/37726845 http://dx.doi.org/10.1186/s13073-023-01229-9

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