Real-World Treatment Patterns and Treatment Benefits among Adult Patients with Atopic Dermatitis: Results from the Atopic Dermatitis Patient Satisfaction and Unmet Need Survey

Atopic dermatitis is a chronic inflammatory skin disorder associated with a heterogeneous presentation and considerable disease burden. Exploring atopic dermatitis treatment patterns and patient benefits could improve disease management and patients’ quality of life. This study aimed to describe current and previous atopic dermatitis treatment patterns and patient benefits from those treatments to inform disease management. Data were collected in 10 countries. Adults (n = 1,988) with confirmed moderate-to-severe atopic dermatitis completed a web-based cross-sectional survey. Most patients (86.6%) had body surface area involvement <10%, and therapies used were topical (69.7%), systemic (28.1%), and biologics (2.3%). Most flares were managed by topical monotherapies (73.4%), even in patients with body surface area involvement ≥10%. Treatment expectations were met only partially, or not at all, in 75% of patients. Those with body surface area involvement ≥10% reported lower treatment satisfaction. Overall, this study highlights the unmet medical needs in atopic dermatitis management. SIGNIFICANCE Atopic dermatitis is a skin disorder with considerable symptoms that can negatively affect a person’s quality of life. In this study, 1,988 patients with atopic dermatitis across 10 countries completed a survey to better understand the treatments they were taking, and how they were helping them. Most participants had mild skin symptoms and were using topical remedies only. Notably, three out of four patients said they were not satisfied with their treatments. This number increased in those with more severe symptoms. This study found that the needs of patients with atopic dermatitis are not being met by current treatments.