Cargando…
Serum uric acid and triglycerides in clear cell renal cell carcinoma: A restrospective cross-sectional study
The available evidence on the relationship between serum uric acid and triglycerides in clear cell renal cell carcinoma (ccRCC) is limited. The objective of this study is to investigate whether there is an independent association between serum uric acid and triglycerides in ccRCC, while adjusting fo...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508505/ https://www.ncbi.nlm.nih.gov/pubmed/37713861 http://dx.doi.org/10.1097/MD.0000000000034645 |
_version_ | 1785107551409405952 |
---|---|
author | Yue, Dong Tian, Jun |
author_facet | Yue, Dong Tian, Jun |
author_sort | Yue, Dong |
collection | PubMed |
description | The available evidence on the relationship between serum uric acid and triglycerides in clear cell renal cell carcinoma (ccRCC) is limited. The objective of this study is to investigate whether there is an independent association between serum uric acid and triglycerides in ccRCC, while adjusting for other variables. This cross-sectional study involved 1018 participants with ccRCC, who were admitted to a hospital in China from December 1st, 2013 to January 1st, 2023. The main independent variable investigated was serum uric acid, which was measured at baseline. The dependent variable was triglycerides. Covariates considered in this study included age, sex, body mass index, smoking status, hypertension, diabetes, coronary disease, High-density lipoprotein cholesterol, Low-density lipoprotein cholesterol, Total cholesterol, Blood urea nitrogen, and Creatinine. The study included 1018 participants with an average age of 56.92 ± 10.88 years old, and approximately 68% of them were male. The fully-adjusted linear regression analysis indicated a positive association between serum uric acid levels (100μmol/L) and triglyceride levels (mmol/L) after adjusting for confounding factors (β = 0.13, 95% CI [0.07, 0.18]). Furthermore, a smooth curve was constructed between serum uric acid and triglycerides based on the fully-adjusted model. In patients with ccRCC, there was a positive association between serum uric acid and triglycerides. |
format | Online Article Text |
id | pubmed-10508505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-105085052023-09-20 Serum uric acid and triglycerides in clear cell renal cell carcinoma: A restrospective cross-sectional study Yue, Dong Tian, Jun Medicine (Baltimore) 7300 The available evidence on the relationship between serum uric acid and triglycerides in clear cell renal cell carcinoma (ccRCC) is limited. The objective of this study is to investigate whether there is an independent association between serum uric acid and triglycerides in ccRCC, while adjusting for other variables. This cross-sectional study involved 1018 participants with ccRCC, who were admitted to a hospital in China from December 1st, 2013 to January 1st, 2023. The main independent variable investigated was serum uric acid, which was measured at baseline. The dependent variable was triglycerides. Covariates considered in this study included age, sex, body mass index, smoking status, hypertension, diabetes, coronary disease, High-density lipoprotein cholesterol, Low-density lipoprotein cholesterol, Total cholesterol, Blood urea nitrogen, and Creatinine. The study included 1018 participants with an average age of 56.92 ± 10.88 years old, and approximately 68% of them were male. The fully-adjusted linear regression analysis indicated a positive association between serum uric acid levels (100μmol/L) and triglyceride levels (mmol/L) after adjusting for confounding factors (β = 0.13, 95% CI [0.07, 0.18]). Furthermore, a smooth curve was constructed between serum uric acid and triglycerides based on the fully-adjusted model. In patients with ccRCC, there was a positive association between serum uric acid and triglycerides. Lippincott Williams & Wilkins 2023-09-15 /pmc/articles/PMC10508505/ /pubmed/37713861 http://dx.doi.org/10.1097/MD.0000000000034645 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | 7300 Yue, Dong Tian, Jun Serum uric acid and triglycerides in clear cell renal cell carcinoma: A restrospective cross-sectional study |
title | Serum uric acid and triglycerides in clear cell renal cell carcinoma: A restrospective cross-sectional study |
title_full | Serum uric acid and triglycerides in clear cell renal cell carcinoma: A restrospective cross-sectional study |
title_fullStr | Serum uric acid and triglycerides in clear cell renal cell carcinoma: A restrospective cross-sectional study |
title_full_unstemmed | Serum uric acid and triglycerides in clear cell renal cell carcinoma: A restrospective cross-sectional study |
title_short | Serum uric acid and triglycerides in clear cell renal cell carcinoma: A restrospective cross-sectional study |
title_sort | serum uric acid and triglycerides in clear cell renal cell carcinoma: a restrospective cross-sectional study |
topic | 7300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508505/ https://www.ncbi.nlm.nih.gov/pubmed/37713861 http://dx.doi.org/10.1097/MD.0000000000034645 |
work_keys_str_mv | AT yuedong serumuricacidandtriglyceridesinclearcellrenalcellcarcinomaarestrospectivecrosssectionalstudy AT tianjun serumuricacidandtriglyceridesinclearcellrenalcellcarcinomaarestrospectivecrosssectionalstudy |