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Semimechanistic pharmacokinetic–pharmacodynamic model of tripegfilgrastim for pediatric patients after chemotherapy

Tripegfilgrastim is a long‐acting granulocyte colony‐stimulating factor (G‐CSF) that has been used to prevent chemotherapy‐induced neutropenia in adults. This study aimed to establish a pharmacokinetic (PK)–pharmacodynamic (PD) model to explore the impact of chemotherapy and tripegfilgrastim on abso...

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Detalles Bibliográficos
Autores principales: Lee, Soyoung, Hong, Kyung Taek, Jang, In‐Jin, Yu, Kyung‐Sang, Kang, Hyoung Jin, Oh, Jaeseong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508573/
https://www.ncbi.nlm.nih.gov/pubmed/37559343
http://dx.doi.org/10.1002/psp4.13012