Saliva as a noninvasive sampling matrix for therapeutic drug monitoring of intravenous busulfan in Chinese patients undergoing hematopoietic stem cell transplantation: A prospective population pharmacokinetic and simulation study

Therapeutic drug monitoring (TDM) of busulfan (BU) is currently performed by plasma sampling in patients undergoing hematopoietic stem cell transplantation (HSCT). Saliva samples are considered a noninvasive TDM matrix. Currently, no salivary population pharmacokinetics (PopPKs) model for BU availab...

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Detalles Bibliográficos
Autores principales: Xu, Baohua, Yang, Ting, Zhou, Jianxing, Zheng, You, Wang, Jingting, Liu, Qingxia, Li, Dandan, Zhang, Yifan, Liu, Maobai, Wu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508574/
https://www.ncbi.nlm.nih.gov/pubmed/37491812
http://dx.doi.org/10.1002/psp4.13004

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