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On the interpretation of transcriptome-wide association studies

Transcriptome-wide association studies (TWAS) aim to detect relationships between gene expression and a phenotype, and are commonly used for secondary analysis of genome-wide association study (GWAS) results. Results from TWAS analyses are often interpreted as indicating a genetic relationship betwe...

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Detalles Bibliográficos
Autores principales: de Leeuw, Christiaan, Werme, Josefin, Savage, Jeanne E., Peyrot, Wouter J., Posthuma, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508613/
https://www.ncbi.nlm.nih.gov/pubmed/37676898
http://dx.doi.org/10.1371/journal.pgen.1010921