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Y-27632 acts beyond ROCK inhibition to maintain epidermal stem-like cells in culture

Conditional reprogramming is a cell culture technique that effectively immortalizes epithelial cells with normal genotypes by renewing epidermal stem cells. Y-27632, a compound that promotes conditional reprogramming through an unknown mechanism, was developed to inhibit the two Rho-associated kinas...

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Detalles Bibliográficos
Autores principales:	Witkowski, Travis A., Li, Bin, Andersen, Jason G., Kumar, Bhavna, Mroz, Edmund A., Rocco, James W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508688/ https://www.ncbi.nlm.nih.gov/pubmed/37698512 http://dx.doi.org/10.1242/jcs.260990

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