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Gastruloid-derived primordial germ cell-like cells develop dynamically within integrated tissues

Primordial germ cells (PGCs) are the early embryonic precursors of gametes – sperm and egg cells. PGC-like cells (PGCLCs) can currently be derived in vitro from pluripotent cells exposed to signalling cocktails and aggregated into large embryonic bodies, but these do not recapitulate the native embr...

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Detalles Bibliográficos
Autores principales:	Cooke, Christopher B., Barrington, Christopher, Baillie-Benson, Peter, Nichols, Jennifer, Moris, Naomi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Stem Cells and Regeneration
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508693/ https://www.ncbi.nlm.nih.gov/pubmed/37526602 http://dx.doi.org/10.1242/dev.201790

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