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The Efficacy of Stellate Ganglion Blockade in Herpetic Neuralgia: A Case Report

The varicella-zoster virus can reactivate in patients with impaired cell-mediated immunity, resulting in herpes zoster (HZ) and sometimes in herpetic neuralgia (HN). Stellate ganglion blockade (SGB) has been studied for the treatment of HN and postherpetic neuralgia (PHN), but its effectiveness in p...

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Autores principales: Asimakopoulos, Thalis A, Gika, Athanasia A, Kekelos, Panayotis S, Kouroukli, Irene C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508710/
https://www.ncbi.nlm.nih.gov/pubmed/37731449
http://dx.doi.org/10.7759/cureus.43805
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author Asimakopoulos, Thalis A
Gika, Athanasia A
Kekelos, Panayotis S
Kouroukli, Irene C
author_facet Asimakopoulos, Thalis A
Gika, Athanasia A
Kekelos, Panayotis S
Kouroukli, Irene C
author_sort Asimakopoulos, Thalis A
collection PubMed
description The varicella-zoster virus can reactivate in patients with impaired cell-mediated immunity, resulting in herpes zoster (HZ) and sometimes in herpetic neuralgia (HN). Stellate ganglion blockade (SGB) has been studied for the treatment of HN and postherpetic neuralgia (PHN), but its effectiveness in preventing PHN in patients with acute HZ is not well-established. Here, we present a case of a 75-year-old woman who underwent SGB for HN of the right upper limb. The patient had been treated with antivirals and various analgesics, but adverse effects due to analgesics led to discontinuation of them. After the first application of SGB, the patient experienced significant pain reduction, and after a second application, complete remission of pain was achieved. Nine months later, the patient remained symptom-free and without PHN. The therapeutic potential of SGB in the treatment of HN and its role in preventing PHN requires further investigation.
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spelling pubmed-105087102023-09-20 The Efficacy of Stellate Ganglion Blockade in Herpetic Neuralgia: A Case Report Asimakopoulos, Thalis A Gika, Athanasia A Kekelos, Panayotis S Kouroukli, Irene C Cureus Anesthesiology The varicella-zoster virus can reactivate in patients with impaired cell-mediated immunity, resulting in herpes zoster (HZ) and sometimes in herpetic neuralgia (HN). Stellate ganglion blockade (SGB) has been studied for the treatment of HN and postherpetic neuralgia (PHN), but its effectiveness in preventing PHN in patients with acute HZ is not well-established. Here, we present a case of a 75-year-old woman who underwent SGB for HN of the right upper limb. The patient had been treated with antivirals and various analgesics, but adverse effects due to analgesics led to discontinuation of them. After the first application of SGB, the patient experienced significant pain reduction, and after a second application, complete remission of pain was achieved. Nine months later, the patient remained symptom-free and without PHN. The therapeutic potential of SGB in the treatment of HN and its role in preventing PHN requires further investigation. Cureus 2023-08-20 /pmc/articles/PMC10508710/ /pubmed/37731449 http://dx.doi.org/10.7759/cureus.43805 Text en Copyright © 2023, Asimakopoulos et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Anesthesiology
Asimakopoulos, Thalis A
Gika, Athanasia A
Kekelos, Panayotis S
Kouroukli, Irene C
The Efficacy of Stellate Ganglion Blockade in Herpetic Neuralgia: A Case Report
title The Efficacy of Stellate Ganglion Blockade in Herpetic Neuralgia: A Case Report
title_full The Efficacy of Stellate Ganglion Blockade in Herpetic Neuralgia: A Case Report
title_fullStr The Efficacy of Stellate Ganglion Blockade in Herpetic Neuralgia: A Case Report
title_full_unstemmed The Efficacy of Stellate Ganglion Blockade in Herpetic Neuralgia: A Case Report
title_short The Efficacy of Stellate Ganglion Blockade in Herpetic Neuralgia: A Case Report
title_sort efficacy of stellate ganglion blockade in herpetic neuralgia: a case report
topic Anesthesiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508710/
https://www.ncbi.nlm.nih.gov/pubmed/37731449
http://dx.doi.org/10.7759/cureus.43805
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