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Rosetta Energy Analysis of AlphaFold2 models: Point Mutations and Conformational Ensembles
AlphaFold2’s ability to accurately predict protein structures from a multiple sequence alignment (MSA) has raised many questions about the utility of the models generated in downstream structural analysis. Two outstanding questions are the prediction of the consequences of point mutations and the co...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508732/ https://www.ncbi.nlm.nih.gov/pubmed/37732281 http://dx.doi.org/10.1101/2023.09.05.556364 |