Tauopathy severely disrupts homeostatic set-points in emergent neural dynamics but not in the activity of individual neurons

The homeostatic regulation of neuronal activity is essential for robust computation; key set-points, such as firing rate, are actively stabilized to compensate for perturbations. From this perspective, the disruption of brain function central to neurodegenerative disease should reflect impairments o...

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Detalles Bibliográficos
Autores principales: McGregor, James N., Farris, Clayton A., Ensley, Sahara, Schneider, Aidan, Wang, Chao, Liu, Yuqi, Tu, Jianhong, Elmore, Halla, Ronayne, Keenan D., Wessel, Ralf, Dyer, Eva L., Bhaskaran-Nair, Kiran, Holtzman, David M., Hengen, Keith B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508737/
https://www.ncbi.nlm.nih.gov/pubmed/37732214
http://dx.doi.org/10.1101/2023.09.01.555947

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