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The structure of a C. neoformans polysaccharide motif recognized by protective antibodies: A combined NMR and MD study

Cryptococcus neoformans is a fungal pathogen responsible for cryptococcosis and cryptococcal meningitis. The C. neoformans capsular polysaccharide and shed exopolysaccharide functions both as a key virulence factor and to protect the fungal cell from phagocytosis. Currently, a glycoconjugate of thes...

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Detalles Bibliográficos
Autores principales: Hargett, Audra A., Azurmendi, Hugo F., Crawford, Conor J., Wear, Maggie P., Oscarson, Stefan, Casadevall, Arturo, Freedberg, Darόn I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508755/
https://www.ncbi.nlm.nih.gov/pubmed/37732210
http://dx.doi.org/10.1101/2023.09.06.556507