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The structure of a C. neoformans polysaccharide motif recognized by protective antibodies: A combined NMR and MD study
Cryptococcus neoformans is a fungal pathogen responsible for cryptococcosis and cryptococcal meningitis. The C. neoformans capsular polysaccharide and shed exopolysaccharide functions both as a key virulence factor and to protect the fungal cell from phagocytosis. Currently, a glycoconjugate of thes...
Autores principales: | Hargett, Audra A., Azurmendi, Hugo F., Crawford, Conor J., Wear, Maggie P., Oscarson, Stefan, Casadevall, Arturo, Freedberg, Darόn I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508755/ https://www.ncbi.nlm.nih.gov/pubmed/37732210 http://dx.doi.org/10.1101/2023.09.06.556507 |
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