Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning

Image-based spatial transcriptomics methods enable transcriptome-scale gene expression measurements with spatial information but require complex, manually-tuned analysis pipelines. We present Polaris, an analysis pipeline for image-based spatial transcriptomics that combines deep learning models for...

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Detalles Bibliográficos
Autores principales: Laubscher, Emily, Wang, Xuefei (Julie), Razin, Nitzan, Dougherty, Tom, Xu, Rosalind J., Ombelets, Lincoln, Pao, Edward, Graf, William, Moffitt, Jeffrey R., Yue, Yisong, Valen, David Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508757/
https://www.ncbi.nlm.nih.gov/pubmed/37732188
http://dx.doi.org/10.1101/2023.09.03.556122

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