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PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits

Protein kinase A (PKA) plays essential roles in diverse cellular functions. However, the spatiotemporal dynamics of endogenous PKA upon activation remain debated. The classical model predicts that PKA catalytic subunits dissociate from regulatory subunits in the presence of cAMP, whereas a second mo...

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Detalles Bibliográficos
Autores principales: Xiong, Wei-Hong, Qin, Maozhen, Zhong, Haining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508765/
https://www.ncbi.nlm.nih.gov/pubmed/37732264
http://dx.doi.org/10.1101/2023.09.05.556437