Cargando…
Poor Generalization by Current Deep Learning Models for Predicting Binding Affinities of Kinase Inhibitors
The extreme surge of interest over the past decade surrounding the use of neural networks has inspired many groups to deploy them for predicting binding affinities of drug-like molecules to their receptors. A model that can accurately make such predictions has the potential to screen large chemical...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508770/ https://www.ncbi.nlm.nih.gov/pubmed/37732243 http://dx.doi.org/10.1101/2023.09.04.556234 |