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The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks

Homologous Recombination (HR) is a high-fidelity repair mechanism of DNA Double-Strand Breaks (DSBs), which are induced by irradiation, genotoxic chemicals or physiological DNA damaging processes. DSBs are also generated as intermediates during the repair of interstrand crosslinks (ICLs). In this co...

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Detalles Bibliográficos
Autores principales: van de Kooij, Bert, van der Wal, Fenna J., Rother, Magdalena B., Creixell, Pau, Stout, Merula, Wiegant, Wouter, Joughin, Brian A., Vornberger, Julia, van Vugt, Marcel A.T.M., Altmeyer, Matthias, Yaffe, Michael B., van Attikum, Haico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508776/
https://www.ncbi.nlm.nih.gov/pubmed/37732274
http://dx.doi.org/10.1101/2023.09.05.556391