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A blood biomarker of accelerated aging in the body associates with worse structural integrity in the brain: replication across three cohorts

Biological aging is the correlated decline of multi-organ system integrity central to the etiology of many age-related diseases. A novel epigenetic measure of biological aging, DunedinPACE, is associated with cognitive dysfunction, incident dementia, and mortality. Here, we tested for associations b...

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Detalles Bibliográficos
Autores principales:	Whitman, Ethan T., Ryan, Calen P., Abraham, Wickliffe C., Addae, Angela, Corcoran, David L., Elliott, Maxwell L., Hogan, Sean, Ireland, David, Keenan, Ross, Knodt, Annchen R., Melzer, Tracy R., Poulton, Richie, Ramrakha, Sandhya, Sugden, Karen, Williams, Benjamin S., Zhou, Jiayi, Hariri, Ahmad R., Belsky, Daniel W., Moffitt, Terrie E., Caspi, Avshalom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508789/ https://www.ncbi.nlm.nih.gov/pubmed/37732266 http://dx.doi.org/10.1101/2023.09.06.23295140

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