A Nanopore sequencing-based pharmacogenomic panel to personalize tuberculosis drug dosing

RATIONALE: Standardized dosing of anti-tubercular (TB) drugs leads to variable plasma drug levels, which are associated with adverse drug reactions, delayed treatment response, and relapse. Mutations in genes affecting drug metabolism explain considerable interindividual pharmacokinetic variability;...

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Detalles Bibliográficos
Autores principales: Verma, Renu, da Silva, Kesia Esther, Rockwood, Neesha, Wasmann, Roeland E., Yende, Nombuso, Song, Taeksun, Kim, Eugene, Denti, Paolo, Wilkinson, Robert. J., Andrews, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508808/
https://www.ncbi.nlm.nih.gov/pubmed/37732197
http://dx.doi.org/10.1101/2023.09.08.23295248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508808/
https://www.ncbi.nlm.nih.gov/pubmed/37732197
http://dx.doi.org/10.1101/2023.09.08.23295248

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