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A Nanopore sequencing-based pharmacogenomic panel to personalize tuberculosis drug dosing
RATIONALE: Standardized dosing of anti-tubercular (TB) drugs leads to variable plasma drug levels, which are associated with adverse drug reactions, delayed treatment response, and relapse. Mutations in genes affecting drug metabolism explain considerable interindividual pharmacokinetic variability;...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508808/ https://www.ncbi.nlm.nih.gov/pubmed/37732197 http://dx.doi.org/10.1101/2023.09.08.23295248 |