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Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome
OBJECTIVE: Obstructive sleep apnea syndrome is associated with many chronic diseases. METHODS: Obesity and thyroid function tests were evaluated retrospectively and cross-sectionally for 782 obstructive sleep apnea syndrome patients. RESULTS: The mean patient age was 49.3±11.5 years, and the majorit...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Associação Médica Brasileira
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508951/ https://www.ncbi.nlm.nih.gov/pubmed/37729367 http://dx.doi.org/10.1590/1806-9282.20230376 |
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author | Duksal, Faysal Eren, Fettah |
author_facet | Duksal, Faysal Eren, Fettah |
author_sort | Duksal, Faysal |
collection | PubMed |
description | OBJECTIVE: Obstructive sleep apnea syndrome is associated with many chronic diseases. METHODS: Obesity and thyroid function tests were evaluated retrospectively and cross-sectionally for 782 obstructive sleep apnea syndrome patients. RESULTS: The mean patient age was 49.3±11.5 years, and the majority were obese (67.9%) or overweight (26.6%). The mean age of the patients in Group 2 (moderate/severe obstructive sleep apnea syndrome) was higher than that of Group 1 (simple snoring/mild obstructive sleep apnea syndrome). The rate of severe obstructive sleep apnea syndrome among obese patients (35.2%) was significantly higher than that of normal-weight (11.6%) and overweight (18.3%) patients (p=0.001). The oxygen desaturation index/apnea-hypopnea index and levels of leukocytes and C-reactive protein were significantly higher, while mean/minimum saturation values and hemoglobin, hematocrit, and free triiodothyronine levels were significantly lower among obese patients compared with overweight and normal-weight patients (p=0.001). Leukocytes, C-reactive protein, and apnea-hypopnea index/oxygen desaturation index values were higher, and mean/minimum saturation values were lower in Group 2 than in Group 1. CONCLUSION: There were relationships between obstructive sleep apnea syndrome severity and body mass index. Obesity could be a critical predisposing factor for sleep disturbances. The prevention and control of obesity is important while being treated for obstructive sleep apnea syndrome. |
format | Online Article Text |
id | pubmed-10508951 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Associação Médica Brasileira |
record_format | MEDLINE/PubMed |
spelling | pubmed-105089512023-09-20 Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome Duksal, Faysal Eren, Fettah Rev Assoc Med Bras (1992) Original Article OBJECTIVE: Obstructive sleep apnea syndrome is associated with many chronic diseases. METHODS: Obesity and thyroid function tests were evaluated retrospectively and cross-sectionally for 782 obstructive sleep apnea syndrome patients. RESULTS: The mean patient age was 49.3±11.5 years, and the majority were obese (67.9%) or overweight (26.6%). The mean age of the patients in Group 2 (moderate/severe obstructive sleep apnea syndrome) was higher than that of Group 1 (simple snoring/mild obstructive sleep apnea syndrome). The rate of severe obstructive sleep apnea syndrome among obese patients (35.2%) was significantly higher than that of normal-weight (11.6%) and overweight (18.3%) patients (p=0.001). The oxygen desaturation index/apnea-hypopnea index and levels of leukocytes and C-reactive protein were significantly higher, while mean/minimum saturation values and hemoglobin, hematocrit, and free triiodothyronine levels were significantly lower among obese patients compared with overweight and normal-weight patients (p=0.001). Leukocytes, C-reactive protein, and apnea-hypopnea index/oxygen desaturation index values were higher, and mean/minimum saturation values were lower in Group 2 than in Group 1. CONCLUSION: There were relationships between obstructive sleep apnea syndrome severity and body mass index. Obesity could be a critical predisposing factor for sleep disturbances. The prevention and control of obesity is important while being treated for obstructive sleep apnea syndrome. Associação Médica Brasileira 2023-09-18 /pmc/articles/PMC10508951/ /pubmed/37729367 http://dx.doi.org/10.1590/1806-9282.20230376 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Duksal, Faysal Eren, Fettah Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome |
title | Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome |
title_full | Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome |
title_fullStr | Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome |
title_full_unstemmed | Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome |
title_short | Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome |
title_sort | evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508951/ https://www.ncbi.nlm.nih.gov/pubmed/37729367 http://dx.doi.org/10.1590/1806-9282.20230376 |
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