Cargando…

Translating genomic tools to Raman spectroscopy analysis enables high-dimensional tissue characterization on molecular resolution

Spatial transcriptomics of histological sections have revolutionized research in life sciences and enabled unprecedented insights into genetic processes involved in tissue reorganization. However, in contrast to genomic analysis, the actual biomolecular composition of the sample has fallen behind, l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sigle, Manuel, Rohlfing, Anne-Katrin, Kenny, Martin, Scheuermann, Sophia, Sun, Na, Graeßner, Ulla, Haug, Verena, Sudmann, Jessica, Seitz, Christian M., Heinzmann, David, Schenke-Layland, Katja, Maguire, Patricia B., Walch, Axel, Marzi, Julia, Gawaz, Meinrad Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509269/ https://www.ncbi.nlm.nih.gov/pubmed/37726278 http://dx.doi.org/10.1038/s41467-023-41417-0

Ejemplares similares

Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring
por: Becker, Lucas, et al.
Publicado: (2021)

Exploring the relationship between epigenetic DNA methylation and cardiac fibrosis through Raman microspectroscopy
por: Becker, Lucas, et al.
Publicado: (2023)

Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms
por: Sugiyama, Kaori, et al.
Publicado: (2021)

Raman spectroscopy in biomedicine – non-invasive in vitro analysis of cells and extracellular matrix components in tissues
por: Brauchle, Eva, et al.
Publicado: (2013)

Raman Microspectroscopy Identifies Biochemical Activation Fingerprints in THP-1- and PBMC-Derived Macrophages
por: Feuerer, Nora, et al.
Publicado: (2022)

Cell death stages in single apoptotic and necrotic cells monitored by Raman microspectroscopy
por: Brauchle, Eva, et al.
Publicado: (2014)

Raman Spectroscopic Analyses of Jaw Periosteal Cell Mineralization
por: Brauchle, Eva, et al.
Publicado: (2017)

Lipidome profiling with Raman microspectroscopy identifies macrophage response to surface topographies of implant materials
por: Feuerer, Nora, et al.
Publicado: (2021)

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
por: Votteler, Miriam, et al.
Publicado: (2012)

Non-invasive detection of DNA methylation states in carcinoma and pluripotent stem cells using Raman microspectroscopy and imaging
por: Daum, Ruben, et al.
Publicado: (2019)

Imaging of α-Synuclein Aggregates in a Rat Model of Parkinson’s Disease Using Raman Microspectroscopy
por: Sevgi, Fide, et al.
Publicado: (2021)

Enabling Multiphoton and Second Harmonic Generation Imaging in Paraffin-Embedded and Histologically Stained Sections
por: Monaghan, Michael G., et al.
Publicado: (2016)

Prospects for regenerative medicine approaches in women's health
por: Schenke‐Layland, Katja, et al.
Publicado: (2015)

Surface functionalization of electrospun scaffolds using recombinant human decorin attracts circulating endothelial progenitor cells
por: Hinderer, Svenja, et al.
Publicado: (2018)

Imaging fibrosis in inflammatory diseases: targeting the exposed extracellular matrix
por: Beziere, Nicolas, et al.
Publicado: (2019)

Generation and Assessment of Functional Biomaterial Scaffolds for Applications in Cardiovascular Tissue Engineering and Regenerative Medicine
por: Hinderer, Svenja, et al.
Publicado: (2015)

Monitoring the macrophage response towards biomaterial implants using label-free imaging
por: Lu, Chuan-en, et al.
Publicado: (2023)

Controlled Heterotypic Pseudo-Islet Assembly of Human β-Cells and Human Umbilical Vein Endothelial Cells Using Magnetic Levitation
por: Urbanczyk, Max, et al.
Publicado: (2020)

Impaired Myocardial Function Is Prognostic for Severe Respiratory Failure in the Course of COVID-19 Infection
por: Petersen-Uribe, Alvaro, et al.
Publicado: (2021)

A Collagen-based Scaffold Delivering Exogenous MicroRNA-29B to Modulate Extracellular Matrix Remodeling
por: Monaghan, Michael, et al.
Publicado: (2014)

A Crucial Role of Glycoprotein VI for Platelet Recruitment to the Injured Arterial Wall In Vivo
por: Massberg, Steffen, et al.
Publicado: (2003)

Impaired cardiac function is associated with mortality in patients with acute COVID-19 infection
por: Rath, Dominik, et al.
Publicado: (2020)

Platelets and Inflammation
por: Gawaz, Meinrad
Publicado: (2005)

Data-Driven Identification of Biomarkers for In Situ Monitoring of Drug Treatment in Bladder Cancer Organoids
por: Becker, Lucas, et al.
Publicado: (2022)

Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development
por: Monaghan, Michael G., et al.
Publicado: (2016)

CD147 is a Novel Interaction Partner of Integrin αMβ2 Mediating Leukocyte and Platelet Adhesion
por: Heinzmann, David, et al.
Publicado: (2020)

ECG changes after percutaneous edge‐to‐edge mitral valve repair
por: Bo, Hou, et al.
Publicado: (2019)

Right-sided infective endocarditis in association with a left-to-right shunt complicated by haemoptysis and acute renal failure: a case report
por: Hellwege, Rubi Stephani, et al.
Publicado: (2020)

Platelet-Derived PCSK9 Is Associated with LDL Metabolism and Modulates Atherothrombotic Mechanisms in Coronary Artery Disease
por: Petersen-Uribe, Álvaro, et al.
Publicado: (2021)

ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury
por: Rohlfing, Anne-Katrin, et al.
Publicado: (2022)

Applying phasor approach analysis of multiphoton FLIM measurements to probe the metabolic activity of three-dimensional in vitro cell culture models
por: Lakner, Pirmin H., et al.
Publicado: (2017)

Exogenous miR-29B Delivery Through a Hyaluronan-Based Injectable System Yields Functional Maintenance of the Infarcted Myocardium
por: Monaghan, Michael G., et al.
Publicado: (2018)

Non-Invasive Three-Dimensional Cell Analysis in Bioinks by Raman Imaging
por: Marzi, Julia, et al.
Publicado: (2022)

Characterization of GPVI- or GPVI-CD39-Coated Nanoparticles and Their Impact on In Vitro Thrombus Formation
por: Nestele, Jeremy A., et al.
Publicado: (2021)

Large-scale lipidomics profiling reveals characteristic lipid signatures associated with an increased cardiovascular risk
por: Harm, Tobias, et al.
Publicado: (2023)

An Unusual Cause of Dyspnea and Thoracic Pressure
por: Chakkalakal, Claire, et al.
Publicado: (2019)

Cocaine and COVID-19 in ST-Elevation Myocardial Infarction
por: Appenzeller, Florian, et al.
Publicado: (2022)

Epigenetic Regulation of Myogenic Gene Expression by Heterochromatin Protein 1 Alpha
por: Sdek, Patima, et al.
Publicado: (2013)

Complement Factor H Loss in RPE Cells Causes Retinal Degeneration in a Human RPE-Porcine Retinal Explant Co-Culture Model
por: Armento, Angela, et al.
Publicado: (2021)

Deceleration capacity is associated with acute respiratory distress syndrome in COVID-19
por: Mizera, Lars, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pafos91bm0f27c3lqqv3l7c8pb