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Community‐acquired Stenotrophomonas maltophilia bacteremia in liver cirrhosis: A case report

Stenotrophomonas maltophilia is a Gram‐negative bacterium, usually considered a nosocomial pathogen. Its role in community‐acquired infections has been reported, but it is still not typically included in differential diagnoses of patients not exposed to the healthcare system. Recently, some reports...

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Autores principales: Shirakura, Kentaro, Saijo, Masaji, Yamada, Tatsuya, Song, Myeongcheol, Constantine, Shadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509336/
https://www.ncbi.nlm.nih.gov/pubmed/37736476
http://dx.doi.org/10.1002/ccr3.7920
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author Shirakura, Kentaro
Saijo, Masaji
Yamada, Tatsuya
Song, Myeongcheol
Constantine, Shadia
author_facet Shirakura, Kentaro
Saijo, Masaji
Yamada, Tatsuya
Song, Myeongcheol
Constantine, Shadia
author_sort Shirakura, Kentaro
collection PubMed
description Stenotrophomonas maltophilia is a Gram‐negative bacterium, usually considered a nosocomial pathogen. Its role in community‐acquired infections has been reported, but it is still not typically included in differential diagnoses of patients not exposed to the healthcare system. Recently, some reports suggested that liver diseases might also act as a possible risk factor for community‐acquired S. maltophilia bloodstream infection. We report a case of a 77‐year‐old woman with a history of cirrhosis who was diagnosed with community‐acquired S. maltophilia bloodstream infection. S. maltophilia not only causes hospital‐acquired infections but is also emerging as a pathogen in community settings. Although community‐onset infection is still rare and might have lower mortality, this antibiotic‐resistant bacterial species should be considered a possible pathogen in patients with liver cirrhosis. Although trimethoprim‐sulfamethoxazole is considered the first‐line treatment, a study in vitro and a 4‐year review of S. maltophilia susceptibility in our institution found that the bacteria were more susceptible to minocycline than to trimethoprim‐sulfamethoxazole. Therefore, minocycline might become the first‐line treatment in the future.
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spelling pubmed-105093362023-09-21 Community‐acquired Stenotrophomonas maltophilia bacteremia in liver cirrhosis: A case report Shirakura, Kentaro Saijo, Masaji Yamada, Tatsuya Song, Myeongcheol Constantine, Shadia Clin Case Rep Case Report Stenotrophomonas maltophilia is a Gram‐negative bacterium, usually considered a nosocomial pathogen. Its role in community‐acquired infections has been reported, but it is still not typically included in differential diagnoses of patients not exposed to the healthcare system. Recently, some reports suggested that liver diseases might also act as a possible risk factor for community‐acquired S. maltophilia bloodstream infection. We report a case of a 77‐year‐old woman with a history of cirrhosis who was diagnosed with community‐acquired S. maltophilia bloodstream infection. S. maltophilia not only causes hospital‐acquired infections but is also emerging as a pathogen in community settings. Although community‐onset infection is still rare and might have lower mortality, this antibiotic‐resistant bacterial species should be considered a possible pathogen in patients with liver cirrhosis. Although trimethoprim‐sulfamethoxazole is considered the first‐line treatment, a study in vitro and a 4‐year review of S. maltophilia susceptibility in our institution found that the bacteria were more susceptible to minocycline than to trimethoprim‐sulfamethoxazole. Therefore, minocycline might become the first‐line treatment in the future. John Wiley and Sons Inc. 2023-09-19 /pmc/articles/PMC10509336/ /pubmed/37736476 http://dx.doi.org/10.1002/ccr3.7920 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shirakura, Kentaro
Saijo, Masaji
Yamada, Tatsuya
Song, Myeongcheol
Constantine, Shadia
Community‐acquired Stenotrophomonas maltophilia bacteremia in liver cirrhosis: A case report
title Community‐acquired Stenotrophomonas maltophilia bacteremia in liver cirrhosis: A case report
title_full Community‐acquired Stenotrophomonas maltophilia bacteremia in liver cirrhosis: A case report
title_fullStr Community‐acquired Stenotrophomonas maltophilia bacteremia in liver cirrhosis: A case report
title_full_unstemmed Community‐acquired Stenotrophomonas maltophilia bacteremia in liver cirrhosis: A case report
title_short Community‐acquired Stenotrophomonas maltophilia bacteremia in liver cirrhosis: A case report
title_sort community‐acquired stenotrophomonas maltophilia bacteremia in liver cirrhosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509336/
https://www.ncbi.nlm.nih.gov/pubmed/37736476
http://dx.doi.org/10.1002/ccr3.7920
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