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Matching-adjusted indirect comparison of the pelabresib-ruxolitinib combination vs JAKi monotherapy in myelofibrosis
Janus kinase inhibitors (JAKis) ruxolitinib, fedratinib, and pacritinib are the current standard of care in symptomatic myelofibrosis (MF). However, progressive disease and toxicities frequently lead to JAKi discontinuation. Preclinical data indicate that combining JAK and bromodomain and extratermi...
Autores principales: | Gupta, Vikas, Mascarenhas, John, Kremyanskaya, Marina, Rampal, Raajit K., Talpaz, Moshe, Kiladjian, Jean-Jacques, Vannucchi, Alessandro M., Verstovsek, Srdan, Colak, Gozde, Dey, Debarshi, Harrison, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509667/ https://www.ncbi.nlm.nih.gov/pubmed/37530627 http://dx.doi.org/10.1182/bloodadvances.2023010628 |
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