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Global and local fat effects on bone mass and quality in obesity: insights from lipidomics and 3D imaging assessment

AIMS: The aim of this study was to investigate the global and local impact of fat on bone in obesity by using the diet-induced obese (DIO) mouse model. METHODS: In this study, we generated a diet-induced mouse model of obesity to conduct lipidomic and 3D imaging assessments of bone marrow fat, and e...

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Detalles Bibliográficos
Autores principales: Dai, Xin, Liu, Beizhong, Hou, Qingtao, Dai, Qijie, Wang, Di, Xie, Bo, Sun, Yue, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509721/
https://www.ncbi.nlm.nih.gov/pubmed/37728005
http://dx.doi.org/10.1302/2046-3758.129.BJR-2023-0102.R1