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Giant retroperitoneal well differentiated liposarcoma: A case report and literature review

INTRODUCTION AND IMPORTANCE: The most prevalent type of primary retroperitoneal tumors is soft tissue sarcoma (STS). Liposarcoma accounts for 40 % of retroperitoneal tumors (Mack, 1995). Retroperitoneal liposarcoma accounts for 12 % to 40 % of all liposarcomas (Vijay and Ram, 2015). They typically p...

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Autores principales: Nureta, Tilahun Habte, Shale, Wongel Tena, Belete, Tewodros Deneke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509818/
https://www.ncbi.nlm.nih.gov/pubmed/37647755
http://dx.doi.org/10.1016/j.ijscr.2023.108679
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author Nureta, Tilahun Habte
Shale, Wongel Tena
Belete, Tewodros Deneke
author_facet Nureta, Tilahun Habte
Shale, Wongel Tena
Belete, Tewodros Deneke
author_sort Nureta, Tilahun Habte
collection PubMed
description INTRODUCTION AND IMPORTANCE: The most prevalent type of primary retroperitoneal tumors is soft tissue sarcoma (STS). Liposarcoma accounts for 40 % of retroperitoneal tumors (Mack, 1995). Retroperitoneal liposarcoma accounts for 12 % to 40 % of all liposarcomas (Vijay and Ram, 2015). They typically present with advanced disease and often carry a poor prognosis. Because of their rarity and anatomic location, these malignant tumors can cause a diagnostic dilemma and present several therapeutic challenges (Vijay and Ram, 2015). CASE PRESENTATION: A 48-year-old male patient presented to our gastrointestinal oncology clinic with a 2-year history of abdominal discomfort, weight loss and steadily growing abdominal swelling. A soft, rubbery lobulated mass with a positive “slippage sign” was palpable over all the quadrants of the abdomen. CT scan conclusion was retroperitoneal lipoma with internal enhancing nodular components. During laparotomy, a fatty mass measuring 55*60*22 cm and weighing 14 kg was excised. Histopathologic report showed a well differentiated liposarcoma (WDLS). CLINICAL DISCUSSION: Giant retroperitoneal liposarcoma (RPL) is exceedingly rare. Liposarcomas have diverse MRI and CT appearances due to the various subtypes. WDLS are difficult to identify from lipomas before surgery. Histopathology is the only way to provide a reliable diagnosis; therefore en block resection is the recommended approach when malignancy cannot be ruled out. CONCLUSION: Although imaging with ultrasound, CT, and MRI can aid in the diagnosis, differentiating WDLS from lipoma pre-operatively can be difficult, and en block resection is the recommended approach when malignancy cannot be ruled out.
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spelling pubmed-105098182023-09-21 Giant retroperitoneal well differentiated liposarcoma: A case report and literature review Nureta, Tilahun Habte Shale, Wongel Tena Belete, Tewodros Deneke Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: The most prevalent type of primary retroperitoneal tumors is soft tissue sarcoma (STS). Liposarcoma accounts for 40 % of retroperitoneal tumors (Mack, 1995). Retroperitoneal liposarcoma accounts for 12 % to 40 % of all liposarcomas (Vijay and Ram, 2015). They typically present with advanced disease and often carry a poor prognosis. Because of their rarity and anatomic location, these malignant tumors can cause a diagnostic dilemma and present several therapeutic challenges (Vijay and Ram, 2015). CASE PRESENTATION: A 48-year-old male patient presented to our gastrointestinal oncology clinic with a 2-year history of abdominal discomfort, weight loss and steadily growing abdominal swelling. A soft, rubbery lobulated mass with a positive “slippage sign” was palpable over all the quadrants of the abdomen. CT scan conclusion was retroperitoneal lipoma with internal enhancing nodular components. During laparotomy, a fatty mass measuring 55*60*22 cm and weighing 14 kg was excised. Histopathologic report showed a well differentiated liposarcoma (WDLS). CLINICAL DISCUSSION: Giant retroperitoneal liposarcoma (RPL) is exceedingly rare. Liposarcomas have diverse MRI and CT appearances due to the various subtypes. WDLS are difficult to identify from lipomas before surgery. Histopathology is the only way to provide a reliable diagnosis; therefore en block resection is the recommended approach when malignancy cannot be ruled out. CONCLUSION: Although imaging with ultrasound, CT, and MRI can aid in the diagnosis, differentiating WDLS from lipoma pre-operatively can be difficult, and en block resection is the recommended approach when malignancy cannot be ruled out. Elsevier 2023-08-22 /pmc/articles/PMC10509818/ /pubmed/37647755 http://dx.doi.org/10.1016/j.ijscr.2023.108679 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Nureta, Tilahun Habte
Shale, Wongel Tena
Belete, Tewodros Deneke
Giant retroperitoneal well differentiated liposarcoma: A case report and literature review
title Giant retroperitoneal well differentiated liposarcoma: A case report and literature review
title_full Giant retroperitoneal well differentiated liposarcoma: A case report and literature review
title_fullStr Giant retroperitoneal well differentiated liposarcoma: A case report and literature review
title_full_unstemmed Giant retroperitoneal well differentiated liposarcoma: A case report and literature review
title_short Giant retroperitoneal well differentiated liposarcoma: A case report and literature review
title_sort giant retroperitoneal well differentiated liposarcoma: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509818/
https://www.ncbi.nlm.nih.gov/pubmed/37647755
http://dx.doi.org/10.1016/j.ijscr.2023.108679
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