Successful use of mepolizumab for severe hypereosinophilic vasculitis with c-ANCA positivity in a previously healthy 7-year-old boy

An unusual case of a pediatric patient with severe eosinophilic vasculitis causing digital ischemia is reported. The patient responded well to the anti–IL-5 agent mepolizumab, lending support for use of mepolizumab in pediatric patients with hypereosinophilic syndromes.

Detalles Bibliográficos
Autores principales: Fox, Eryn, Cohen, Barrie, Treyster, Zoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509853/
https://www.ncbi.nlm.nih.gov/pubmed/37780105
http://dx.doi.org/10.1016/j.jacig.2022.09.009
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author Fox, Eryn
Cohen, Barrie
Treyster, Zoya
author_facet Fox, Eryn
Cohen, Barrie
Treyster, Zoya
author_sort Fox, Eryn
collection PubMed
description An unusual case of a pediatric patient with severe eosinophilic vasculitis causing digital ischemia is reported. The patient responded well to the anti–IL-5 agent mepolizumab, lending support for use of mepolizumab in pediatric patients with hypereosinophilic syndromes.
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spelling pubmed-105098532023-09-29 Successful use of mepolizumab for severe hypereosinophilic vasculitis with c-ANCA positivity in a previously healthy 7-year-old boy Fox, Eryn Cohen, Barrie Treyster, Zoya J Allergy Clin Immunol Glob Case Report An unusual case of a pediatric patient with severe eosinophilic vasculitis causing digital ischemia is reported. The patient responded well to the anti–IL-5 agent mepolizumab, lending support for use of mepolizumab in pediatric patients with hypereosinophilic syndromes. Elsevier 2022-10-30 /pmc/articles/PMC10509853/ /pubmed/37780105 http://dx.doi.org/10.1016/j.jacig.2022.09.009 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Fox, Eryn
Cohen, Barrie
Treyster, Zoya
Successful use of mepolizumab for severe hypereosinophilic vasculitis with c-ANCA positivity in a previously healthy 7-year-old boy
title Successful use of mepolizumab for severe hypereosinophilic vasculitis with c-ANCA positivity in a previously healthy 7-year-old boy
title_full Successful use of mepolizumab for severe hypereosinophilic vasculitis with c-ANCA positivity in a previously healthy 7-year-old boy
title_fullStr Successful use of mepolizumab for severe hypereosinophilic vasculitis with c-ANCA positivity in a previously healthy 7-year-old boy
title_full_unstemmed Successful use of mepolizumab for severe hypereosinophilic vasculitis with c-ANCA positivity in a previously healthy 7-year-old boy
title_short Successful use of mepolizumab for severe hypereosinophilic vasculitis with c-ANCA positivity in a previously healthy 7-year-old boy
title_sort successful use of mepolizumab for severe hypereosinophilic vasculitis with c-anca positivity in a previously healthy 7-year-old boy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509853/
https://www.ncbi.nlm.nih.gov/pubmed/37780105
http://dx.doi.org/10.1016/j.jacig.2022.09.009
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