Blister fluid as a cellular input for ex vivo diagnostics in drug-induced severe cutaneous adverse reactions improves sensitivity and explores immunopathogenesis

BACKGROUND: Drug-induced severe cutaneous adverse reactions (SCARs) are presumed T-cell–mediated hypersensitivities associated with significant morbidity and mortality. Traditional in vivo testing methods, such as patch or intradermal testing, are limited by a lack of standardization and poor sensit...

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Detalles Bibliográficos
Autores principales: Awad, Andrew, Mouhtouris, Effie, Nguyen-Robertson, Catriona Vi, Holmes, Natasha, Chua, Kyra Y.L., Copaescu, Ana, James, Fiona, Goh, Michelle S., Aung, Ar Kar., Godfrey, Dale I., Philips, Elizabeth J., Gibson, Andrew, Almeida, Catarina F., Trubiano, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509900/
https://www.ncbi.nlm.nih.gov/pubmed/37780076
http://dx.doi.org/10.1016/j.jacig.2021.11.001

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