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Endogenous inhibitory mechanisms in asthma
Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E(2), prostaglandin I(2), lipoxins, resolvins, protectins, maresins, gluc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509980/ https://www.ncbi.nlm.nih.gov/pubmed/37781649 http://dx.doi.org/10.1016/j.jacig.2023.100135 |
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author | Chiarella, Sergio E. Barnes, Peter J. |
author_facet | Chiarella, Sergio E. Barnes, Peter J. |
author_sort | Chiarella, Sergio E. |
collection | PubMed |
description | Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E(2), prostaglandin I(2), lipoxins, resolvins, protectins, maresins, glucagon-like peptide-1 receptor, adrenomedullin, nitric oxide, and carbon monoxide. Here we review the most recent literature regarding these endogenous inhibitory mechanisms in asthma, which remain a promising target for the prevention and treatment of asthma. |
format | Online Article Text |
id | pubmed-10509980 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-105099802023-09-29 Endogenous inhibitory mechanisms in asthma Chiarella, Sergio E. Barnes, Peter J. J Allergy Clin Immunol Glob Review Article Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E(2), prostaglandin I(2), lipoxins, resolvins, protectins, maresins, glucagon-like peptide-1 receptor, adrenomedullin, nitric oxide, and carbon monoxide. Here we review the most recent literature regarding these endogenous inhibitory mechanisms in asthma, which remain a promising target for the prevention and treatment of asthma. Elsevier 2023-07-05 /pmc/articles/PMC10509980/ /pubmed/37781649 http://dx.doi.org/10.1016/j.jacig.2023.100135 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Chiarella, Sergio E. Barnes, Peter J. Endogenous inhibitory mechanisms in asthma |
title | Endogenous inhibitory mechanisms in asthma |
title_full | Endogenous inhibitory mechanisms in asthma |
title_fullStr | Endogenous inhibitory mechanisms in asthma |
title_full_unstemmed | Endogenous inhibitory mechanisms in asthma |
title_short | Endogenous inhibitory mechanisms in asthma |
title_sort | endogenous inhibitory mechanisms in asthma |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509980/ https://www.ncbi.nlm.nih.gov/pubmed/37781649 http://dx.doi.org/10.1016/j.jacig.2023.100135 |
work_keys_str_mv | AT chiarellasergioe endogenousinhibitorymechanismsinasthma AT barnespeterj endogenousinhibitorymechanismsinasthma |