Cargando…

Endogenous inhibitory mechanisms in asthma

Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E(2), prostaglandin I(2), lipoxins, resolvins, protectins, maresins, gluc...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiarella, Sergio E., Barnes, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509980/
https://www.ncbi.nlm.nih.gov/pubmed/37781649
http://dx.doi.org/10.1016/j.jacig.2023.100135
_version_ 1785107868975890432
author Chiarella, Sergio E.
Barnes, Peter J.
author_facet Chiarella, Sergio E.
Barnes, Peter J.
author_sort Chiarella, Sergio E.
collection PubMed
description Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E(2), prostaglandin I(2), lipoxins, resolvins, protectins, maresins, glucagon-like peptide-1 receptor, adrenomedullin, nitric oxide, and carbon monoxide. Here we review the most recent literature regarding these endogenous inhibitory mechanisms in asthma, which remain a promising target for the prevention and treatment of asthma.
format Online
Article
Text
id pubmed-10509980
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-105099802023-09-29 Endogenous inhibitory mechanisms in asthma Chiarella, Sergio E. Barnes, Peter J. J Allergy Clin Immunol Glob Review Article Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E(2), prostaglandin I(2), lipoxins, resolvins, protectins, maresins, glucagon-like peptide-1 receptor, adrenomedullin, nitric oxide, and carbon monoxide. Here we review the most recent literature regarding these endogenous inhibitory mechanisms in asthma, which remain a promising target for the prevention and treatment of asthma. Elsevier 2023-07-05 /pmc/articles/PMC10509980/ /pubmed/37781649 http://dx.doi.org/10.1016/j.jacig.2023.100135 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Chiarella, Sergio E.
Barnes, Peter J.
Endogenous inhibitory mechanisms in asthma
title Endogenous inhibitory mechanisms in asthma
title_full Endogenous inhibitory mechanisms in asthma
title_fullStr Endogenous inhibitory mechanisms in asthma
title_full_unstemmed Endogenous inhibitory mechanisms in asthma
title_short Endogenous inhibitory mechanisms in asthma
title_sort endogenous inhibitory mechanisms in asthma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509980/
https://www.ncbi.nlm.nih.gov/pubmed/37781649
http://dx.doi.org/10.1016/j.jacig.2023.100135
work_keys_str_mv AT chiarellasergioe endogenousinhibitorymechanismsinasthma
AT barnespeterj endogenousinhibitorymechanismsinasthma