Eosinophil trafficking in allergen-mediated pulmonary inflammation relies on IL-13–driven CCL-11 and CCL-24 production by tissue fibroblasts and myeloid cells

BACKGROUND: The immunologic mechanisms underlying pulmonary type 2 inflammation, including the dynamics of eosinophil recruitment to the lungs, still need to be elucidated. OBJECTIVE: We sought to investigate how IL-13–producing T(H)2 effector cells trigger eosinophil migration in house dust mite (H...

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Detalles Bibliográficos
Autores principales: Gazzinelli-Guimaraes, Pedro H., Golec, Dominic P., Karmele, Erik P., Sciurba, Joshua, Bara-Garcia, Pablo, Hill, Tom, Kang, Byunghyun, Bennuru, Sasisekhar, Schwartzberg, Pamela L., Nutman, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509988/
https://www.ncbi.nlm.nih.gov/pubmed/37781651
http://dx.doi.org/10.1016/j.jacig.2023.100131

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