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Exploring Celiac Disease: A Case Analysis of Multi-Systemic Symptoms and Effective Dietary Intervention in a Young Female

This study presents the case of a 23-year-old woman diagnosed with celiac disease (CD), a condition triggered by an immune response to gluten, leading to inflammation in the small intestine. The patient manifested typical gastrointestinal symptoms, including diarrhea, abdominal pain, and vomiting, c...

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Autores principales: Ahmed, Mahmoud, Sunkara, Vyshnavidevi, Khan, Muhammad S, Affaf, Maryam, Anwaar, Mohammad Ahsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510008/
https://www.ncbi.nlm.nih.gov/pubmed/37736457
http://dx.doi.org/10.7759/cureus.43839
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author Ahmed, Mahmoud
Sunkara, Vyshnavidevi
Khan, Muhammad S
Affaf, Maryam
Anwaar, Mohammad Ahsan
author_facet Ahmed, Mahmoud
Sunkara, Vyshnavidevi
Khan, Muhammad S
Affaf, Maryam
Anwaar, Mohammad Ahsan
author_sort Ahmed, Mahmoud
collection PubMed
description This study presents the case of a 23-year-old woman diagnosed with celiac disease (CD), a condition triggered by an immune response to gluten, leading to inflammation in the small intestine. The patient manifested typical gastrointestinal symptoms, including diarrhea, abdominal pain, and vomiting, complemented by extra-intestinal signs such as fatigue and skin rashes. Diagnosis was corroborated through the presence of tTG-IgA antibodies and distinct histological changes in the duodenum. A notable finding was the patient's iron deficiency anemia, directly linked to the duodenal damage caused by CD. Effective management, encompassing a strict gluten-free diet and iron supplementation, resulted in marked improvement in her condition. This case accentuates the significance of early CD detection, especially in patients exhibiting a combination of gastrointestinal and extra-intestinal symptoms. Emphasis is placed on the pivotal role of timely diagnosis, adherence to a gluten-free regimen, and sustained monitoring to ensure patient well-being and prevent complications.
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spelling pubmed-105100082023-09-21 Exploring Celiac Disease: A Case Analysis of Multi-Systemic Symptoms and Effective Dietary Intervention in a Young Female Ahmed, Mahmoud Sunkara, Vyshnavidevi Khan, Muhammad S Affaf, Maryam Anwaar, Mohammad Ahsan Cureus Family/General Practice This study presents the case of a 23-year-old woman diagnosed with celiac disease (CD), a condition triggered by an immune response to gluten, leading to inflammation in the small intestine. The patient manifested typical gastrointestinal symptoms, including diarrhea, abdominal pain, and vomiting, complemented by extra-intestinal signs such as fatigue and skin rashes. Diagnosis was corroborated through the presence of tTG-IgA antibodies and distinct histological changes in the duodenum. A notable finding was the patient's iron deficiency anemia, directly linked to the duodenal damage caused by CD. Effective management, encompassing a strict gluten-free diet and iron supplementation, resulted in marked improvement in her condition. This case accentuates the significance of early CD detection, especially in patients exhibiting a combination of gastrointestinal and extra-intestinal symptoms. Emphasis is placed on the pivotal role of timely diagnosis, adherence to a gluten-free regimen, and sustained monitoring to ensure patient well-being and prevent complications. Cureus 2023-08-21 /pmc/articles/PMC10510008/ /pubmed/37736457 http://dx.doi.org/10.7759/cureus.43839 Text en Copyright © 2023, Ahmed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Ahmed, Mahmoud
Sunkara, Vyshnavidevi
Khan, Muhammad S
Affaf, Maryam
Anwaar, Mohammad Ahsan
Exploring Celiac Disease: A Case Analysis of Multi-Systemic Symptoms and Effective Dietary Intervention in a Young Female
title Exploring Celiac Disease: A Case Analysis of Multi-Systemic Symptoms and Effective Dietary Intervention in a Young Female
title_full Exploring Celiac Disease: A Case Analysis of Multi-Systemic Symptoms and Effective Dietary Intervention in a Young Female
title_fullStr Exploring Celiac Disease: A Case Analysis of Multi-Systemic Symptoms and Effective Dietary Intervention in a Young Female
title_full_unstemmed Exploring Celiac Disease: A Case Analysis of Multi-Systemic Symptoms and Effective Dietary Intervention in a Young Female
title_short Exploring Celiac Disease: A Case Analysis of Multi-Systemic Symptoms and Effective Dietary Intervention in a Young Female
title_sort exploring celiac disease: a case analysis of multi-systemic symptoms and effective dietary intervention in a young female
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510008/
https://www.ncbi.nlm.nih.gov/pubmed/37736457
http://dx.doi.org/10.7759/cureus.43839
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