Cargando…
Colitis-induced upregulation of tumor necrosis factor receptor-2 (TNFR2) terminates epithelial regenerative signaling to restore homeostasis
Colonic epithelial repair is a key determinant of health. Repair involves changes in epithelial differentiation, an extensive proliferative response, and upregulation of regeneration-associated “fetal-like” transcripts, including Ly6a (Sca-1), that represent Yap1 and interferon targets. However, lit...
Autores principales: | Sharifkhodaei, Zohreh, Liu, Cambrian Y., Girish, Nandini, Huang, Ying, Punit, Shivesh, Washington, M. Kay, Polk, D. Brent |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510063/ https://www.ncbi.nlm.nih.gov/pubmed/37736049 http://dx.doi.org/10.1016/j.isci.2023.107829 |
Ejemplares similares
-
TNF Receptor 1 Promotes Early-Life Immunity and Protects against Colitis in Mice
por: Liu, Cambrian Y., et al.
Publicado: (2020) -
Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice
por: Dubé, Philip E., et al.
Publicado: (2018) -
Targeted Colonic Claudin-2 Expression Renders Resistance to Epithelial Injury, Induces Immune Suppression and Protects from Colitis
por: Ahmad, Rizwan, et al.
Publicado: (2014) -
Tumor Necrosis Factor Receptor 2 (TNFR2): An Emerging Target in Cancer Therapy
por: Medler, Juliane, et al.
Publicado: (2022) -
Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis
por: Siegmund, Daniela, et al.
Publicado: (2016)