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Colitis-induced upregulation of tumor necrosis factor receptor-2 (TNFR2) terminates epithelial regenerative signaling to restore homeostasis

Colonic epithelial repair is a key determinant of health. Repair involves changes in epithelial differentiation, an extensive proliferative response, and upregulation of regeneration-associated “fetal-like” transcripts, including Ly6a (Sca-1), that represent Yap1 and interferon targets. However, lit...

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Detalles Bibliográficos
Autores principales: Sharifkhodaei, Zohreh, Liu, Cambrian Y., Girish, Nandini, Huang, Ying, Punit, Shivesh, Washington, M. Kay, Polk, D. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510063/
https://www.ncbi.nlm.nih.gov/pubmed/37736049
http://dx.doi.org/10.1016/j.isci.2023.107829

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