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Small volume bone marrow aspirates with high progenitor cell concentrations maximize cell therapy dose manufacture and substantially reduce donor hemoglobin loss

BACKGROUND: Bone marrow (BM) transplantation is a life-saving therapy for hematological diseases, and the BM harbors also highly useful (progenitor) cell types for novel cell therapies manufacture. Yet, the BM collection technique is not standardized. METHODS: Benchmarking our collection efficiency...

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Detalles Bibliográficos
Autores principales: Epah, Jeremy, Spohn, Gabriele, Preiß, Kathrin, Müller, Markus M., Dörr, Johanna, Bauer, Rainer, Daqiq-Mirdad, Shabnam, Schwäble, Joachim, Bernas, Stefanie N., Schmidt, Alexander H., Seifried, Erhard, Schäfer, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510270/
https://www.ncbi.nlm.nih.gov/pubmed/37726769
http://dx.doi.org/10.1186/s12916-023-03059-3

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