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Small volume bone marrow aspirates with high progenitor cell concentrations maximize cell therapy dose manufacture and substantially reduce donor hemoglobin loss
BACKGROUND: Bone marrow (BM) transplantation is a life-saving therapy for hematological diseases, and the BM harbors also highly useful (progenitor) cell types for novel cell therapies manufacture. Yet, the BM collection technique is not standardized. METHODS: Benchmarking our collection efficiency...
Autores principales: | Epah, Jeremy, Spohn, Gabriele, Preiß, Kathrin, Müller, Markus M., Dörr, Johanna, Bauer, Rainer, Daqiq-Mirdad, Shabnam, Schwäble, Joachim, Bernas, Stefanie N., Schmidt, Alexander H., Seifried, Erhard, Schäfer, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510270/ https://www.ncbi.nlm.nih.gov/pubmed/37726769 http://dx.doi.org/10.1186/s12916-023-03059-3 |
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