Polymorphism at codon 31 of CDKN1A (p21) as a predictive factor for bevacizumab therapy in glioblastoma multiforme

Glioblastoma (GBM), a prevalent and malignant brain tumor, poses a challenge in surgical resection due to its invasive nature within the brain parenchyma. CDKN1A (p21, Waf-1), a cyclin-dependent kinase inhibitor, plays a pivotal role in regulating cell growth arrest, terminal differentiation, and ap...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Yu, Shen, Chiung-Chyi, Liang, Yea-Jiuen, Chiao, Ming-Tsang, Yang, Yi-Chin, Hsieh, Wan-Yu, Lin, Cheng-Hui, Chen, Jun-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510274/
https://www.ncbi.nlm.nih.gov/pubmed/37730565
http://dx.doi.org/10.1186/s12885-023-11400-5

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