Umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles ameliorate cutaneous wound healing in type 2 diabetic mice via macrophage pyroptosis inhibition

BACKGROUND: Delayed healing of diabetic cutaneous wounds is one of the most common complications of type 2 diabetes mellitus (T2DM), which can bring great distress to patients. In diabetic patients, macrophages accumulate around skin wounds and produce NLRP3 (NOD-, LRR-, and pyrin domain-containing...

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Detalles Bibliográficos
Autores principales: Wang, Yiming, Jing, Lin, Lei, Xiao, Ma, Zhen, Li, Bei, Shi, Yuanyuan, Zhang, Wuyang, Li, Yuan, Zhou, Hongzhi, Hu, Kaijin, Xue, Yang, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510296/
https://www.ncbi.nlm.nih.gov/pubmed/37726853
http://dx.doi.org/10.1186/s13287-023-03490-6

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