Cargando…
NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors
[Image: see text] NADPH oxidases (NOXs) form a family of electron-transporting membrane enzymes whose main function is reactive oxygen species (ROS) generation. Strong evidence suggests that ROS produced by NOX enzymes are major contributors to oxidative damage under pathologic conditions. Therefore...
Autores principales: | Cipriano, Alessandra, Viviano, Monica, Feoli, Alessandra, Milite, Ciro, Sarno, Giuliana, Castellano, Sabrina, Sbardella, Gianluca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510401/ https://www.ncbi.nlm.nih.gov/pubmed/37650225 http://dx.doi.org/10.1021/acs.jmedchem.3c00770 |
Ejemplares similares
-
Lysine methyltransferase inhibitors: where we are now
por: Feoli, Alessandra, et al.
Publicado: (2021) -
Discovery of Benzo[d]imidazole‐6‐sulfonamides as Bromodomain and Extra‐Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain
por: Cipriano, Alessandra, et al.
Publicado: (2022) -
The emerging role of lysine methyltransferase SETD8 in human diseases
por: Milite, Ciro, et al.
Publicado: (2016) -
Identification
of a Protein Arginine Methyltransferase
7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor
por: Feoli, Alessandra, et al.
Publicado: (2023) -
Turning Nonselective
Inhibitors of Type I Protein
Arginine Methyltransferases into Potent and Selective Inhibitors of
Protein Arginine Methyltransferase 4 through a Deconstruction–Reconstruction
and Fragment-Growing Approach
por: Iannelli, Giulia, et al.
Publicado: (2022)