Synthesis and Structure–Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents

[Image: see text] The continuing prevalence of drug-resistant tuberculosis threatens global TB control programs, highlighting the need to discover new drug candidates to feed the drug development pipeline. In this study, we describe a high-throughput screening hit (4-benzylpiperidin-1-yl)(1-(5-pheny...

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Detalles Bibliográficos
Autores principales: Yadav, Veena D., Boshoff, Helena I., Trifonov, Lena, Roma, Jose Santinni O., Ioerger, Thomas R., Barry, Clifton E., Oh, Sangmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510505/
https://www.ncbi.nlm.nih.gov/pubmed/37736177
http://dx.doi.org/10.1021/acsmedchemlett.3c00295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510505/
https://www.ncbi.nlm.nih.gov/pubmed/37736177
http://dx.doi.org/10.1021/acsmedchemlett.3c00295

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