Stabilisation of the RirA [4Fe–4S] cluster results in loss of iron-sensing function

RirA is a global iron regulator in diverse Alphaproteobacteria that belongs to the Rrf2 superfamily of transcriptional regulators, which can contain an iron–sulfur (Fe–S) cluster. Under iron-replete conditions, RirA contains a [4Fe–4S] cluster, enabling high-affinity binding to RirA-regulated operat...

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Detalles Bibliográficos
Autores principales: Gray, Elizabeth, Stewart, Melissa Y. Y., Hanwell, Libby, Crack, Jason C., Devine, Rebecca, Stevenson, Clare E. M., Volbeda, Anne, Johnston, Andrew W. B., Fontecilla-Camps, Juan C., Hutchings, Matthew I., Todd, Jonathan D., Le Brun, Nick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510648/
https://www.ncbi.nlm.nih.gov/pubmed/37736639
http://dx.doi.org/10.1039/d3sc03020b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510648/
https://www.ncbi.nlm.nih.gov/pubmed/37736639
http://dx.doi.org/10.1039/d3sc03020b

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