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Dual Input-Controlled Synthetic mRNA Circuit for Bidirectional Protein Expression Regulation
[Image: see text] Synthetic mRNA circuits manipulate cell fate by controlling output protein expression via cell-specific input molecule detection. Most current circuits either repress or enhance output production upon input binding. Such binary input–output mechanisms restrict the fine-tuning of pr...
Autores principales: | Tan, Kaixin, Hu, Yaxin, Liang, Zhenghua, Li, Cheuk Yin, Yau, Wai Laam, Kuang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510700/ https://www.ncbi.nlm.nih.gov/pubmed/37652441 http://dx.doi.org/10.1021/acssynbio.3c00144 |
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